This may be helpful to all who have tested their Y-STRs. I've understood
for awhile that DYS464 is considered a volatile marker and not terribly
reliable. I did not know, however, that FTDNA has been sloppy in its
reporting of it. I'd think this is well-worth the $9.95. I'm ordering it.
Judging from some of this wording, I suspect Astrid Krahn is not a native
English speaker. I won't hold that against her. :) She does seem to have a
flair for drama.
-Michael
---------------------------- Original Message ----------------------------
Subject: July 4th is DYS464 Day
From: "YSEQ DNA Shop" <shop_at_yseq.net>
Date: Thu, July 3, 2014 7:07 pm
To: "Michael Cooley" <michael_at_newsummer.com>
--------------------------------------------------------------------------
Dear YSEQ customer,
The 4th of July 1776 has changed the American history. The people didn't
want to be ruled by what was then considered as the "evil empire", so they
made an important step forward and took their lives under their own
control. Empires come and go. When structures of power are too entangled,
it sometimes needs a courageous leader who steps away from crusted
structures and starts a small revolution.
The current situation in genetic genealogy is similar. There is only one
big provider who holds almost the complete genealogical Y-STR database in
his hands. So far there is nothing wrong with this, as long as the data is
accessible for the genealogists who need it. However since there is no
competition, the big provider has become lazy with further developments
and with fixing long term mistakes in the STR database. Implementing
micro-alleles in the database or adding some simple rules that consider
palindromic recombination events should be a minimum standard for an
informative Y-STR database. In fact a significant increase of mistakes has
been reported by customers during the last year that mainly involve
micro-alleles, null alleles and palindromic Y-STR markers.
This is where we need to take action now! DYS464 is the biggest hotspot of
errors in Y-STR databases. It's time to clean out the DYS464 mistakes from
your projects. DYS464 has normally 4 alleles, but sometimes there are 8 or
up to 12 alleles at this palindromic marker. Therefore YSEQ has a special
offer from July 4th to July 12th where you can order DYS464X for $9.95,
the price of a normal STR marker! This is not only the unsorted alleles,
but we also report the L464 SNP status of each STR allele which is
important in R1b. And that's even not all, you also get the DYF399X marker
for FREE in the XTD panel! This is a very fast mutating 3 copy Y-STR
marker that you can use to work out closely related haplotypes in your
project and it also makes it easier to recognize and explain duplications
and deletions in the palindromic region due to the asymmetric structure of
this DYF399 marker.
This is your opportunity as a project administrator to mobilize your
project participants to get this informative double pack of DYS464X and
DYF399X at the price of a breakfast in a coffee shop! Really, everybody
should be able to afford this. Here is the direct link to the XTD panel:
http://shop.yseq.net/product_info.php?products_id=2179
YSEQ-XTD Panel Sale
Contains DYS464X and DYF399X
Only $9.95 (instead of $25)
Only from July 4th to July 12th
Declare your independence from clumsy DYS464 results. Let your DYS464 get
analyzed by the inventors of the DYS464X test! And if you have already
your sample at YSEQ, don't forget to use the coupon code IDONTNEEDAKIT !
Thank you very much for your continued support!
Astrid Krahn
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--
VP, the Cooley Family Association of America
Administrator, the Akins DNA Project
Administrator, the Ashenhurst DNA Project
Administrator, the Bishop DNA Project
Administrator, the Eldridge DNA Project
Administrator, the Fisk DNA Project
Administrator, the alt-McDowell DNA Project
Co-Administrator, the Cooley DNA Project
Co-Administrator, the McDougall DNA Project
Co-Administrator, the Pickens DNA Project
Co-Administrator, the Strother DNA Project
Instructor, the Osher Lifelong Learning Institute (OLLI)
B.A. Humboldt State University, History
Received on Thu Jul 03 2014 - 23:27:33 CDT